Recent critical health events, such as e-cigarette or vaping product use-associated lung injury and the COVID-19 pandemic, highlight the importance of examining how tobacco and nicotine products may influence and interact with respiratory health. This special issue from the journal of Nicotine & Tobacco Research on respiratory disease associations with cigarettes and noncigarette nicotine and tobacco use includes a collection of multidisciplinary studies that begin to examine the effect of tobacco and nicotine use from the cellular level to patterns of use and symptomology at the population level.
Resources for Researchers
Explore databases and tools for research to support the regulation of tobacco and tobacco products.
A catalog of recommended standard measures of phenotypes and environmental exposures for use in biomedical research. This includes common data elements for tobacco regulatory research.
Learn more about the PhenX Tobacco Regulatory Project and how these measures were identified, selected, and approved.
Provides a variety of research chemicals, controlled substances, marijuana cigarettes, and nicotine research cigarettes to investigators working in the area of drug abuse, addiction, and related disciplines.
Access to information about active research projects in the FDA Center for Tobacco Products research portfolio.
Ongoing and timely information about emerging public health issues in smoking and tobacco use control from the National Cancer Institute.
Regulatory Research Information
This guidance will assist investigators who are seeking to request Investigational Tobacco Products (ITP) authorization or information to determine whether an ITP is needed when administering tobacco products to human study participants.
Answers to common questions about clinical studies of e-cigarettes examining a potential therapeutic purpose (e.g., smoking cessation), which may require an investigational new drug application. Such studies are not funded through TRSP.
Addresses the importance of tobacco research, research advances, funding opportunities, and ways to use the research.
Video interviews with leading researchers in tobacco regulatory research who share their work and discuss its importance to public health.
Tobacco Regulatory Science: Research To Inform Regulatory Action at the Food and Drug Administration’s Center for Tobacco Products
Clarifies the definition and role of regulatory science and describes the types of research efforts that will inform the FDA’s public health framework for tobacco product regulation.
This document provides points to consider regarding applications from grantees that also receive support from the tobacco industry or their related entities. While this guidance was originally issued for NIDA applicants, it is relevant for all applications submitted in response to TRSP funding opportunity announcements.